New research reveals that R-ketamine can restore brain activity and social functioning in isolated mice, offering a potential intervention for social impairments linked to prolonged loneliness. The study highlights the importance of the anterior insular cortex and suggests that R-ketamine may be more effective than S-ketamine in improving social cognition.
Key Points
R-ketamine uniquely reactivates the anterior insular cortex region in isolated mice
Improvement in social memory and sociability observed in treated mice
Properly functioning aIC circuits are vital for the benefits of R-ketamine
Pros
R-ketamine restores brain activity and social functioning in isolated mice
Potential intervention for social impairments linked to prolonged loneliness
Improves social cognition and sociability in treated mice
Cons
More research is needed to fully understand the effects of R-ketamine
Loneliness and depression rates continue to rise globally