A high-fat diet may contribute to the development of Alzheimer’s disease by affecting levels of certain tiny molecules called miRNAs in the brain and body. These miRNAs could be potential targets for new Alzheimer’s drugs or diagnostic tests.
Key Points
High-fat diet alters levels of key miRNAs in the brain and body
Certain miRNAs like miR-19a-3p, miR-34a, and miR-146a are affected by the diet
miR-29c may play a protective role against Alzheimer’s in response to high-fat diet
Pros
Identified potential link between high-fat diet, miRNAs, and Alzheimer’s disease
Highlights possible new targets for Alzheimer’s drugs or diagnostic tests
Cons
Study conducted on mice, may not directly translate to humans