The Impact of Visceral Fat on Brain Health
New research from Toho University in Japan suggests that visceral fat plays a role in maintaining brain health through a chemical messaging system involving the protein CX3CL1, which helps regulate BDNF levels. The study found that as mice aged, both their belly fat and brain's BDNF levels decreased, impacting cognitive function. The researchers emphasize the importance of a balanced approach to belly fat, as both too little and too much can have negative health consequences.
Key Points
- Visceral fat produces CX3CL1, which helps regulate BDNF levels in the brain
- A decline in belly fat-derived CX3CL1 with age can contribute to memory problems
- A balance in belly fat levels is crucial for optimal brain health
Pros
- Reveals a previously unknown communication system between belly fat and the brain
- Provides insights into how visceral fat can play a role in maintaining brain health through the production of CX3CL1
- Opens up possibilities for future therapeutic interventions to slow cognitive decline
Cons
- Research conducted in mice, so direct translation to humans is not fully understood
- Small sample sizes used in the study
- Limitations in directly testing the impact of changes in fat-derived CX3CL1 on memory or cognitive abilities